Autosomal recessive pedigree chart: sickle cell disease
Two carriers have affected, carrier and unaffected children; the loaded example shows AA, AS and SS genotypes.
Add relatives, mark affected people and carriers, and draw a pedigree with standard symbols.
Teaching examples with typical patterns. Real families need assessment by a genetics professional.
Two carriers have affected, carrier and unaffected children; the loaded example shows AA, AS and SS genotypes.
Affected people appear in each generation, including father-to-son transmission and a presymptomatic carrier.
A carrier mother has affected and unaffected sons; a carrier daughter passes the variant to her son.
An affected grandfather has carrier daughters; an affected father and a carrier mother have an affected daughter.
An affected father passes the trait to all daughters; an affected mother has affected and unaffected children.
Maternal transmission with variable expression; affected fathers do not pass on mitochondrial variants.
An illustrative Y-linked trait passes from fathers to sons, while daughters are unaffected.
First cousins are linked with a double relationship line; an affected child appears in generation IV.
Symbols represent gender identity; optional notes record sex assigned at birth.
Based on NSGC standardized pedigree nomenclature: Bennett et al., 2008; 2022 gender-inclusive revision and 2025 correction.
Select a person in the preview or use the dropdown.
Build the family or paste a PED-style table.
Check the legend and genotypes before sharing.
Typical clues for reading a pedigree chart; these patterns alone do not establish a diagnosis.
| Inheritance pattern | Typical clue |
|---|---|
| Autosomal dominant |
|
| Autosomal recessive |
|
| X-linked recessive |
|
| X-linked dominant |
|
| Mitochondrial |
|
| Y-linked |
|
A pedigree chart, or pedigree diagram, is a genetic diagram of family relationships and how a trait appears across generations. A family pedigree chart uses standard symbols, relationship lines and a legend to explain the information recorded.
Squares, circles and diamonds represent gender identity. Filled symbols mark affected people; half-filled symbols or central dots mark carriers. An arrow with P identifies the proband. The legend explains the symbols used in your chart.
Start with relatives and their relationships, then mark affected people and known carriers. For a sickle cell pedigree chart, optional AA, AS and SS labels show hemoglobin genotypes. Show two carrier parents with half-filled symbols and fill the affected child completely. The same drawing conventions apply to cystic fibrosis and PKU. To start from a template, load the sickle cell example and edit the people and statuses.
Show affected males with filled squares and carrier females with a central dot or half-fill. There is no father-to-son transmission. A real family’s inheritance pattern needs assessment by a genetics professional.
Yes. Enter a genotype for each person and turn on Show genotypes. The sickle cell example includes AA, AS and SS; use the notation appropriate to the condition you are describing.
Paste a pedigree table in CSV or TSV format with id, father, mother, sex and affected columns. Five-column PED-style tables and PLINK FAM/PED rows with FID, IID, PAT, MAT, SEX and PHENO are also accepted. Additional genotype columns in PLINK rows are ignored.
A genetic pedigree records biological relationships and the distribution of a trait. A genogram can include wider social and emotional relationships. A family tree usually focuses on ancestry rather than standardized genetic symbols.
Identify the proband with an arrow and P, explain the condition and carrier markings in the legend, and define abbreviations in the caption. Use initials or study identifiers instead of full names. Check consent and your journal’s requirements. SVG can be edited in PowerPoint or Illustrator.
Yes. This free pedigree chart maker needs no account for PNG and SVG downloads. The chart is drawn in your browser: names and health details are not uploaded, and the draft stays in this browser tab. Edit in canvas needs a free account. A temporary copy passes the chart to the canvas and is deleted when the canvas opens it; unused copies expire after 30 minutes and are cleared the next time you open this tool, or if the canvas tries to open an expired copy. The canvas keeps its working draft in this browser. Saving it stores the chart in your account, exporting sends it to our server to build the file, and using the canvas AI assistant sends the chart's content to the AI provider.
Add relatives and record the information you know.